Starting Strattera: What to Expect Week by Week
First Week: Early Effects and Initial Adjustment
Those first few days can feel like stepping into slightly different shoes — subtle, sometimes surprising. Mild nausea, dry mouth, or jittery nerves may appear as your body adapts. Keep a simple diary of timing and symptoms so you can discuss any patterns with your clinician at follow-up.
Expect attention and focus to shift rather than flip instantly; some days feel clearer, others fuzzy. By day seven you might glimpse Noticable mental steadiness, but full benefits often take longer. Report severe or worsening symptoms promptly, and keep communicating with your prescriber.
Week Two: Tracking Focus and Mood Shifts

In the second week many people start noticing small shifts: concentration can feel steadier and moments of hyperfocus may soften. I remember waking up and managing a short task list more calmly. strattera's slow buildup means changes are subtle, not sudden.
Mood can fluctuate — some days brighter, others flat — and it helps to log patterns. Note times of improved attention and any irritability; these notes give your clinician useful data. Try keeping entries brief and consistent each day.
If negative feelings intensify or daily function worsens, contact your prescriber. Otherwise, expect gradual continuity into week three as the brain acommodate the new chemistry, celebrate small wins and continue with patience along the way.
Week Three: Sleep, Appetite, and Energy Changes
A few nights in, sleep can feel unpredictable — dreams may be sharper, some fall asleep easier, while others wake more. These shifts are common with strattera as your body adjusts and usually settle over time.
Appetite often changes: you might eat less at first or crave different foods, which can slightly alter weight. Keep a food log to spot patterns and maintain nutrition.
Energy levels may fluctuate; some often report clearer mornings and very mild afternoon dips. Gentle exercise and steady sleep routines help make progress more Noticable.
If insomnia, severe appetite loss, or exhaustion interfere with daily life, contact your prescriber promptly — dose tweaks or timing adjustments can help, and tracking improves managment decisions.
Weeks Four to Six: Noticeable Cognitive Improvements Begin

Around the one-month mark many people begin to notice clearer thinking and improved task persistence. Small daily victories—finishing emails, following conversations—feel more frequent, and the fog that once slowed decisions starts lifting. These cognitive gains with strattera are gradual, not instant, but patience rewards progress indeed.
Concentration windows lengthen and working memory often strengthens, letting you hold points in mind while planning. Tasks that used to require multiple starts often finish with fewer interruptions. Improvement is noticable in everyday problem solving, though stress or poor sleep can still reduce gains over time too.
Keep tracking what improves and what doesnt: focus, mental speed, and the ability to organize ideas. Journaling brief examples each day helps quantify progress and guides conversations with your clinician about adjustments. Celebrate small wins and maintain realistic expectations as cognitive change often consolidates slowly over months.
Managing Side Effects: When to Call Your Doctor
I remember starting strattera and feeling a flurry of small sensations — dry mouth, slight nausea, faster heartbeat. Most early effects are mild and fade as your body adjusts, but it helps to keep a symptom log and note when issues start, worsen, or improve. Bring this to appointments.
Contact your clinician promptly if you experience chest pain, fainting, severe mood swings, suicidal thoughts, or a sudden and Noticable change in heart rate or blood pressure. For other issues like insomnia, appetite shifts, or headaches, try small lifestyle changes first and call if they persist beyond a week or worsen.
Keep emergency contacts handy, and don't ignore sudden fainting or breathing problems. Your prescriber can adjust dose or suggest switching medications. Trust your instincts — if something feels off, call; timely action can prevent Occassionally overlooked complications and restore comfort much sooner.
Longer Term: Dose Adjustments and What Comes Next
After the first months your clinician will review how you’re doing and consider whether the current dose is right. Some patients need gradual increases to find a balance between benefit and side effects, while others maintain stability. Expect follow-up visits to measure not only focus but mood, blood pressure, and overall daily functioning.
Adjustments are usually based on symptom tracking, side effect profiles, and sometimes lab or heart rate checks. It can take several weeks after a change before improvements are noticable, and clinicians will often wait to see if new symptoms occurence resolve or persist before changing course.
Long-term care emphasizes communication: keep a journal, report mood shifts or appetite changes, and don’t stop medication suddenly. If side effects are unacceptable, alternate strategies or combination therapy may be discussed; shared decision making helps tailor treatment until goals are met. Mayo Clinic NCBI
